You are using an outdated browser. For a faster, safer browsing experience, upgrade for free today.

OCCUPATIONAL DUST PATHOLOGY AND RISK OF DEVELOPMENT OF MALIGNANT TUMORS OF RESPIRATORY ORGANS

https://doi.org/10.33573/ujoh2006.02.008

Nahorna A.M., Varyvonchyk D.V.

OCCUPATIONAL DUST PATHOLOGY AND RISK OF DEVELOPMENT OF MALIGNANT TUMORS OF RESPIRATORY ORGANS

Institute for Occupational Health of AMS of Ukraine, Kiev, Ukraine

Full article (PDF), UKR

The studies showed that the risk of development of bronchi and lungs cancer in patients with pathology of respiratory organs (chronic dust bronchitis, pneumoconiosis) exceeded general population levels by 3—90 times depending on the type and intensity of the effect of harmful work factors. The major harmful occupational factors causing developing the cancer pathol-ogy of respiratory organs (bronchi and lungs) are dusts of silicon dioxide, welding dust containing heavy metals, asbestos, abrasive dust containing silicon dioxide (granite) and metals, aerosols of concentrated acids when exceeding threshold limits by 10—58 times. The manifestation of clinical types of cancer pathology in patients with occupational dust pathology of res-piratory organs is recorded in 2— 11 years after determination of the occupational character of the diseases of the respiratory organs. There were proposed methods for early detection of cancer pathology and medical care of patients with dust pathol¬ogy of respiratory organs of occupational origin.

Key words: occupational pathology of respiratory organs, cancer of bronchi and lungs, risk factors, work condi¬tions, profession

References

  1. Varivonchik D.V. (2005), “Occupational respiratory cancer in Ukraine: Clinical and Statistical Analysis”, Collected works of employees of the KMAPO named after. P.L. Shupik, Issue 14, Part.2, 553-557.
  2. Varivonchik D.V., Nagornaya AM, Gruzova L. M. (2005), “Epidemiological regularities of cancer pathology of respiratory organs of the able-to-work population, depending on working conditions and tobacco smoking”, Mater. conf. "Modern technologies of preservation and strengthening the human health, Kyiv 110-112.
  3. Nahorna A.M.,Krasniuk O.P., Varyvonchyk D.V., Kharzhevska A.M. (2004), “Occupational respiratory cancer of workers of the uranium mining industry of Ukraine: clinical and epidemiological study (1993-2003)”, Gigiena truda, Issue 35, 363-375.
  4. Cancer. (2006), WHO Information bulletin №297, http:/www.who.int/mediacentre/factsheets/fs297/ru/
  5. Fedorenko Z.P.,Hulak L.O.,Horokh E.L..Sumkina O.V.Cancer in Ukraine. 2003-2004. Morbidity, mortality, indicators of the oncology service activity. Bulletin of the National Cancer Register of Ukraine. - К„ 2003.- No 6.- 97 с.
  6. Abrasive blasting agents: designing studies to evaluate relative risk/A.Hubbs, M.Greskevitch. E.Kuempel et al.//J. Toxicol. Environ. Health.- 2005.- V.68, No 11-12.- P. 999-1016. https://doi.org/10.1080/15287390590912612
  7. Agricultural lung disease/J.R.Spurzem. D.J.Rom- berger, S.G.Von Essen//Clin. Chest. Med.- 2002.- V.23, No 4.-P. 795-810. https://doi.org/10.1016/S0272-5231(02)00024-2
  8. Attfield M.D., Costello J. Quantitative exposure- response for silica dust and lung cancer in Vermont granite workers//Am. J. Ind. Med.- 2004,- V.45, No 2.- P. 129-138. https://doi.org/10.1002/ajim.10348
  9. Biological responses of workplace particles and their association with adverse health effects on miners/W.Chen, K.Stempelmann, S.Rehn et al.//J. Environ. Monit.- 2004.-V.6, No12,- P. 967-972. https://doi.org/10.1039/b407606k
  10. Cancer incidence among union carpenters in New Jersey/J.Dement, L.Pompeii, l.M.Lipkus, P.Samsa// J. Occup. Environ. Med.- 2003.- V.45, No 10,-P. 1059-1067. https://doi.org/10.1097/01.jom.0000085892.01486.6a
  11. Cancer incidence and mortality of isocyanate ex­posed workers from the Swedish polyurethane foam industry: updated findings 1959-1998/Z.Mikoczy, Welinder, H.Tinnerberg. L.Hagmar//Occup. Environ. Med - 2004,- V.61, No 5.- P. 432-437. https://doi.org/10.1136/oem.2003.009712
  12. Cancer mortality among European asphalt work­ers: an international epidemiological study. II. Exposure to bitumen fume and other agents/P.Boffetta, Burstyn, T.Partanen et al.//Am. J. Ind. Med.- 2003,- V.43, No 1.- P.28-39.
  13. Finkelstein M.M., Verma D.K. Mortality among Ontario members of the International Union of Bricklayers and Allied Craftworkers//Am. J. Ind. Med.- 2005,- V.47, No 1.-P. 4-9.
  14. Kraus T., Muller-Lux A. Occupation related thora­cic tumors//Radiolog.- 2004,- V.44, No 5.- P. 427-434. https://doi.org/10.1002/ajim.20116
  15. Lung cancer risk in workers exposed to poly{vinyl chloride) dust: a nested case-referent study/ G.Mastrangelo, U.Fedeli, E.Fadda et al.// Occup. Environ. Med.- 2003- V.60, No 6.- P. 423-428. https://doi.org/10.1136/oem.60.6.423
  16. Lung cancer screening - state of the art/ D.Nowak, U.Ochmann, R.M.Huber, S.Diederich// Pneumologie.- 2005.-V.59, No 3.- P. 178-191. https://doi.org/10.1055/s-2004-830200
  17. Meo S.A. Health hazards of cement dust// Saudi. Med. J.- 2004.-V.25. No 9,- P. 1153-1159.
  18. Mortality and cancer incidence of workers in Finnish road paving companies/T.Kauppinen, P.Helk- kila, T.Partanen, S.V.Virtanen//Am. J. Ind. Med.- 2003-V. 43, No 1,- P. 49-57. https://doi.org/10.1002/ajim.10161
  19. Smailyte G., Kurtinaitis J., Andersen A. Mortality and cancer incidence among Lithuanian cement pro­ducing workers//Occup. Environ. Med.- 2004.- V.61, No 6 - P. 529-534. https://doi.org/10.1136/oem.2003.009936