Ukrainian journal of occupational health 3-4 2005

Advantages of bodyplethismography and diffusion capacity in evaluation of lung function condition in patients with pneumoconiosis

Basanets A.V.

Institute for Occupational Health of AMS of Ukraine, Kiev

Full article (PDF), UKR

The problem of pneumoconioses in Ukraine needs for searching and revealing of diagnostic criteria that could be biomark¬ers of the early stage of disease. In the article there are results of lung function investigation of 543 underground miners with Pneumoconioses and 187 miners without bronchopulmonary diseases using spirometry, bodyplethismography and diffusion capacity methods. Analysis of results didn't reveal changes of spirometry indices that are criteria of obstruction. But in patients with pneumoconiosis restrictive changes of lung function were revealed by decreasing of RV. FRC, TLC and DLCO in comparison with the control group and normal levels. So, bodyplethismography is the most informative method for diag¬nostics of respiratory insufficiency in patients with pneumoconioses.

Key words: pneumoconioses, spirometry, bodyplethismography, lung volumes, DLCO


  1. Bauer T.T. Schultze-Werninghaus G.. Kollmeier J. et al. Functional variables associated with the clinical grade of dyspnoea In coal miners with pneumoconiosis and mild bronchial obstruction//Occup. Environ. Med.- 2001V.58. No. 12,- P. 794-799.
  2. Beeckman L.F.. Wang M.L.. Wagner G.R.. Petsonk E.L. Accelerated declines In FEV1 and subsequent increased respiratory symptoms, illnesses, and mortality in coal miners//Am. J. Respir. Crit. Care Med.- 2001.- V. 163.- P. 633-639.
  3. Chi L., Plao Z., Liu Y. Change of pulmonary diffusing capacity, membrane diffusing capacity and pulmonary capillary blood volume In patients with COPD and connective tissue disease at rest and post-exercise// Zhonghua Jie He Hu.- 2001.- V.21. No.6,- P. 344-347.
  4. Collins L.C.. Willing S.. Bretz R. et al. High-resolution CT in simple coal workers' pneumoconiosis. Lack of correlation with pulmonary (unction tests and arterial blood gas values//Chest.- 1993.-V. 104. No.4.- P. 1156-1162.
  5. Cooper J.K.. Johnson T.P Exercise capacity in coal workers' pneumoconiosis: an analysis using causal modeling//Br. J. Ind. Med.- 1990 - V.47. No.1.- P. 52-57.
  6. Gevenois P.A.. Sergent G.. De Maertelaer V. et al. Micronodules and emphysema in coal mine dust or silica exposure: relaton with lung function//Eur. Respir. J.- 1998.-V. 12. No.5-P. 1020-1024.
  7. Lin L.C.. Yang S.C.. Lu K.W. Ventilatory defect in coal workers with simple pneumoconiosis: early detection functional abnormalities//Kaohsiung J. Med. Sc!.- 2001.- V. 17. No.5.- P. 245-252.
  8. Lodi V.. D'Ella V., Campana E. et al. Use of diverse diagnostic techniques in the study of silicosis//G. Ital. Med. Lav. Ergon.- 2000,- V.22. No.1.- P. 3-6.
  9. Marek K. Principles of work capacity assessment in occupational respiratory diseases//Med. Pr.- 2002.- V.53. No.3,- R 245-252.
  10. Nakamura M.. Thkahashi Y.. Ohrui T. et al. Criteria of impairment of pulmonary function using Japanese standard values//Nihon Kokyuki Gakkai Zasshi.- 2002,- V.40, N" 12.- P. 925-992.
  11. Petrova E.. Petkov D.. Shonshkov R. Nachev C. The diagnostic value of conventional X-ray examination of the lungs in comparison with hight-resolution computed tomography (HRCT). isotope perfusion scintigra¬phy and the diffusion capacity in patients with pneu- moconiosis//Int. J. Occup. Med. Plnviron. Health.- 1995,- V.8. No.3.- P. 231-238.
  12. Tjoe-Nij E., MeerG.G.. Smit J.. Heederik D. Lung function desrease in relation to pneumoconiosis and exposure to quartz-containing dust in construction workers//Am. J. Ind. Med.- 2003,- V.43. No.6 - P. 574-583.
  13. Wang X.R.. Christiani D.C. Respiratory symptoms and functional status in wokers exposed to silica, asbestos, and coal mine dust//J. Occup. Environ. Med.- 2002.-V.42. No.11.- P. 1076-1084.
  14. Wang X.. Yu I.T.. WongT.W.. Yano E. Respiratory symptoms and pulmonary function in coal miners: looking into the effects of simple pneumoconiosis//Am. J. Ind. Med.- 1999.-V.35. No.2.-P. 124-131.<124::AID-AJIM3>3.3.CO;2-D