https://doi.org/10.33573/ujoh2005.01.069

Javorovsky A.P., Carvoronskaya M.A.

DELAYED EFFECTS OF BIOLOGICAL ACTION OF POLYMER COMPOUNDS

A.A.Bogomolets National Medical University, Kyiv

Full article (PDF), RUS

A scientific survey on the delayed biological effects of polymer compounds has been carried out. The data have been analyzed on mutagenic and carcinogenic activity, on embryo- and gonadotoxic effects. The results on the delayed effects of the stud¬ied compounds on animals and humans are laid down. The need is expressed to continue studies on this problem in future.

Key words: polymer compounds, epoxide resin, mutagenicity, carcinogenicity

References

  1. Antonova V.I.,Salmina Z.A., Gigiena I sanitaria.- 1977.- No 8.- 78-82.
  2. Anisimova I.G.. Zaprivoda L.P Gigiyenicheskiye voprosy vzaimodeystviya organizma s faktorami okruzhayushchey sredy raznoy prirody.- К.. 1984.- 134-137.
  3. Barilyak I.R.. Anisimov I.G.. Shkvar L.A. //Problema genetiki cheloveka.- Novokuznetsk. 1991.-S. 6-8.
  4. Bokaneva S.A.//Gigiyena vneshney sredy,- Ro tov-na-Donu. 1977.-S. 16-17.
  5. Varshavskaya S.P. Sovremennyye predstavleniya ob otdalennykh effektakh deystviya khimicheskikh zagryazneniy okruzhayushchey sredy//Otdalennyye posledstviya biologicheskogo deystviya nekotorykh khimicheskikh veshchestv, zagryaznyayushchikh okruzhayushchuyu sredu (nauchnyy obzor).- M.. 1975.-S. 8.
  6. Hanul V.D. Rak lehkoho//Likuvannya ta diahnostyka.- 2004,- № 1.- S. 29-33.
  7. Dubinin N.P. Obshchaya genetika.- M.: Nauka. 1970.-S. 300-320.
  8. Zholos V.V. Otdalennyye effekty deystviy epoksidnoy smoly UP-671 //Obl. nauchn. konf. «Dostizheniya molodykh uchenykh-medikov v praktiku zdravookhraneniya»: Tez. dokl,-Donetsk. 1990.-S. 14-15.
  9. Efetov V.M. Rak zheludka//Likuvannya ta diahnostyka,- 2003,- №4.- S. 30-35.
  10. Krasnyuk E.P., Gorban L.N. Problems of detection and prevention of occupational cancer in Ukraine // Proc. "Gigiena truda" .- K. 1999.-No. 30, -P. 103-112.
  11. Kuzmina LP. Bezrukavnikova L.M. // "Gigiena truda" .- K. 1985.- №9.- P. 48-49.
  12. Luk'yanova T.P.. Masterkova Ye.V.//Uchreditel'naya konferentsiya Permskogo oblastnogo obshchestva toksikologov.- Perm'. 1987,-S. 40-41.
  13. Papoyan S.A.. Zil'fyan V.N.. Kumkumadzhyan B.S. i dr. Vozmozhnaya kantserogennaya opasnost' na nekotorykh khimicheskikh proizvodstvakh Armyanskoy SSR//Professional'nyy rak: Sbornik nauchnykh trudov NII gigiyeny im. F.F.Erismana. vyl.2.- M.. 1981.-S. 95-97.
  14. Penknovich A.A.. Kalyaganov P.I. O nekotorykh podkhodakh k izucheniyu otdalennykh posledstviy professional'nykh zabolevaniy//Gig. truda i prof. zabolevaniya,- 1989.-No 5.-S. 43-44.
  15. Sazonova L.F. Mutagennyye effekty u lits, kontaktiruyushchikh s sinteticheskimi smolami//Gig. truda i prof. zabolevaniya.- 1988-№2.- S. 43-45.
  16. Sanotskiy I.V.. Fomenko V.N.//Otdalennyye posledstviya vliyaniya khimicheskikh soyedineniy na organizm.-M.. 1979,-S. 232.
  17. Turusov V.S. Proizvodstvennyye kantserogennyye vrednosti: ikh deystviye na cheloveka i eksperimental'nykh zhivotnykh//Professional'nyy rak: Sbornik nauchnykh trudov NII gigiyeny im. F.F.Erismana. vyp.2.- M.. 1981.-S. 10-14.
  18. Kheminke K.. Falk K.//Voprosy promyshlennoy toksikologii, fiziologii truda i proizvodstvennogo shuma,- M.. 1985.- S. 65-68.
  19. Yablokova A.P. Vozdeystviye stirola na spetsificheskiye funktsii zhenskogo organizma//Professional'nyye zabolevaniya v khimicheskoy promyshlennosti,- M.: Meditsina. 1965.-S. 95-99.
  20. Yavorovskiy A.P. Occupational health in the preparation and processing of epoxy resins and plastics, Abstract, dis .... dr med sciences.- K .. 1990, - 268 p.
  21. Yavorovskiy A.II.. Paustovskiy YU.A. Ob embriotoksicheskom i teratogennom deystvii nekotorykh marok epoksidnykh smol//Líkar. sprava- 1997- №2,-S. 120-123.
  22. Yavorovskiy A.P.. Paustovskiy YU.A. O tsitogeneticheskoy aktivnosti nekotorykh marok epoksidnykh smol//Likap. sprava.- 1996.- №7.- S. 95-98.
  23. Andersen M.//Natune.- 1978.-V.276.-Р. 391-392. https://doi.org/10.1038/276391a0
  24. BoothG.I.//Xenobiotlca.- 1975.-V.5.-P. 197-203.
  25. Brookes R On the interaction of carcinogens with DNA//Blochem. Pharmacol.- 1971.- P. 20. 999. https://doi.org/10.1016/0006-2952(71)90324-8
  26. Blok J.B.//J. Am. Med. ASS.- 1974,- V.229. №1.-P. 53-54.
  27. Shimizu X., Suzuki T. et al. / / Sante igaku.- 1982, - T.244 .- p. 489-503.
  28. Creech J.L.. Johnson M.N.//Occup. Med.- 1974.-V.16 - 150-151.
  29. HammarC.G.. Holmstedt B.. Llndgren J.E., Tamm R. The combination of gas chromatography and mass spectometry in the identification of drugs and metabolites//Adv. Pharmacol. Chemother.- 1969.- P. 7.53. https://doi.org/10.1016/S1054-3589(08)60559-1
  30. Manson M.M.//Br. J. Ind. Med.- 1980.-V.37.- P. 317-336. https://doi.org/10.1136/oem.37.4.317
  31. MaltoniC., Lefemine G.//Environ. Res.- 1974,- V.7. №3.- P. 387-405. https://doi.org/10.1016/0013-9351(74)90040-1
  32. Picciano D. Cytogenetic investigation of occupa­tional exposure to epichlorohydrin//Mut. Res.- 1979,- V.66.-R 169-173. https://doi.org/10.1016/0165-1218(79)90062-4
  33. Gervais R. Chabaux C.. Noeuveglice A.. Besson C. Epitheliomas spino-celluldvines multiples suc­cédant a l'évolution prolongée d'un eczeme de contact aux resines epoxydiques//Arch. Mal. Prof.- 1982.- V.43. №8.- P. 645-658.
  34. Viola P L.//Med. Lavoro.- 1970,- V.61. №3- P.