DOI xxxxxxxx

Kovalenko О.М., Muraviova І.М.

DISORDERS OF THE OSTEOGENESIS HORMONAL REGULATION IN LIQUIDATORS OF CHERNOBYL ACCIDENT WITH HIGH ABSORBED DOSES OF RADIATION FOR THE NEAREST AND DELAYED TERMS AFTER THE RADIATION EXPOSURE

Research Centre of Radiation Medicine of AMS of Ukraine

Full article (PDF), UKR

The results of determination of the basal hormones concentrations, affecting the osteogenesis and bone tissue mineral densi¬ty in persons, irradiated in a wide range of dozes, for the nearest and delayed periods are presented. The osteopenic syndrome by the T-criterion in clean-up workers of ChNPP was recorded more often than in the compared group. The increased con¬centration of the general calcium in clean-up workers of ChNPP can be the result of the increased calcitonin level and, accordingly, by the decreased parathormone level. The average levels of cortisol and testosterone, which nonspecifically affect the metabolism of the bone tissue, differ as well. The obtained results allow to suggest that the radiation factor can affect the bone tissue by the changes of the hormonal regulation systems in its re-modeling and resorption.

Key words: clean-up workers of ChNPP, irradiation absorbed doses, hormonal regulation, bone tissue mineral density

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