Ukrainian journal of occupational health 4(57) 2018
Kapustnyk V. A.1, Zavhorodniy I. V.1, Boeckmann I.2, Litovchenko O. L.1, Lalymenko O. S.1
Experience of international collaboration in solving actual medical and biological problems of occupational health and ecology
1Kharkiv National Medical University
2Magdeburg University named after Otto von Guericke, Germany
Full article (PDF), UKR
Introduction. The multidisciplinarity of scientific problems, which became a subject of investigations in modern occupational medicine, occupational health and ecology, more and more dictates the necessity of establishing creative connections with relevant specialists of foreign, first of all, European, leading educational and scientific institutions and centers.
The purpose of the work is to summarize the results of scientific studies on current medical and biological problems of occupational health and ecology, which are carried out with involvement of mechanisms of international collaboration, including the use of the unified approaches to setting up and conducting experiments, statistical processing of the data, comparative analysis of the results and their testing at international forums.
Materials and methods. The international approach to solving a number of priority problems of modern medicine was used, namely: definition of peculiarities in the development of the state of occupational burnout in workers of socially significant professions; establishing hygienic significance and definition of biological mechanisms of the combined action of physical factors of the environment and work conditions; development of methodological approaches to substantiation of biological maximum permissible concentrations. In order to solve such tasks, which were put in the context of the international collaboration, it was made an Agreement on collaboration between the Chair of Occupational Health at the Medical Faculty of the Magdeburg University named after Otto von Guericke (Germany) and Chairs of Internal and Occupational Diseases; Hygiene and Ecology № 2, of the Kharkiv National Medical University, which has been legally valid since 2012 till present time.
Results. The directions of scientific studies on medical and biological problems of occupational health and ecology are described in the paper, when the tasks are solved with the involvement of mechanisms of the international collaboration. It has been proved that among the workers of socially significant occupations which are exposed to elements of intensive work, there are some symptoms of "burnout" at the level of 42–76 % and the risk of "occupational burnout" at the level of 3–19 % depending on profession, gender, age. In assessing the effect of physical factors of the environment, it was established that the combined effect of electromagnetic radiation and positive low temperatures caused more significant disorders of biochemical and morphological parameters. The methodical basis of biological monitoring of drugs – derivatives of succinic acid was substantiated and the algorithm of differentiated selection of a combination of informative biomarkers was developed for determination of the biological safety level of exposure to these compounds. A biological safety level for an antidiabetic agent in the blood plasma at the level of 11 ng/μl is recommended, which will make it possible to supervise more effectively for sanitary-hygienic control of the influence of this medicinal product in conditions of its industrial production.
Conclusions. The use of the international experience in organizing and conducting studies on actual medical and biological problems in occupational health and ecology has proved its effectiveness at the stages of planning, statistical processing of materials and approbation of the research results at scientific forums.
Кey words: international collaboration, problems of occupational health and ecology, occupational burnout, combined effect of factors, biomonitoring
- Hering T., Beerlage I., and Kleiber D. (2011), "Arbeitsanforderungen und Ressourcen im Rettungsdienst", Z. Gesundheitspsychol., 19 (4), 159–172. https://doi.org/10.1026/0943-8149/a000051
- Jonsson A. and Segesten K. (2004), "Daily stress and concept of self in Swedish ambulance personnel", Prehosp. Disast. Med., 19, 226–234. https://doi.org/10.1017/S1049023X00001825
- Jonsson A. and Segesten K. 2004, "Guilt, shame and need for a container: A study of posttraumatic stress among ambulance personnel", Acc. Emerg. Nurs., 12, 215–233.
- Jonsson A., Segesten K., and Mattson B. (2003), "Posttraumatic stress among Swedish ambulance personnel", Emerg. Med. J., 20, 79–78. https://doi.org/10.1136/emj.20.1.79
- Regehr C., Goldberg G., and Hughes J. (2002), "Exposure to human tragedy, empathy and trauma in ambu lance paramedics", Am. J. Orthopsychiatry, 72, 505–513. https://doi.org/10.1037/0002-9422.214.171.1245
- Teegen F. (1999), "Berufsbedingte Traumatisierung bei Polizei, Feuerwehr und Rettungsdienst", Z. Polit. Psychol., 7 (4), 437–453.
- Wagner D., Heinrichs M., and Ehlert U. (1999), "Prevalence of symptoms of posttraumatic stress disorder in German professional firefighters", Am. J. Psychiatry, 155 (12), 1727–1732. https://doi.org/10.1176/ajp.155.12.1727
- Alexander D. A. and Klein S. (2001), "Ambulance personnel and critical incidents: Impact of accident and emergency work on mental health and emotional well being", Brit. J. Psychiatry, V. 178 (1), 76–81. https://doi.org/10.1192/bjp.178.1.76
- Beaton R., Murphy S., and Pike K. (1996), "Work and nonwork stressors, negative affective states and pain complaints among firefighters and paramedics", Int. J. Stress Manag., 3 (4), 223–237. https://doi.org/10.1007/BF01857685
- Grigsby D. W. and McKnew M. A. (1988), "Work stress burnout among paramedics", Psychol. Rep., V. 63 (1), 55–64. https://doi.org/10.2466/pr0.19126.96.36.199
- Hering T. and Beerlage I. (2004), "Arbeitsbedingungen, Belastungen und Burnout im Rettungsdienst", Notfall Rettungsmed., V. 7 (6), 415–424. https://doi.org/10.1007/s10049-004-0681-7
- Nazari H., Jariani M., Beiranvand S. et al. (2016), "The prevalence of job stress and its relationship with burnout syndrome among the academic members of Lorestan University of Medical sciences", J. Caring Sci., 5 (1), 75–84. https://doi.org/10.15171/jcs.2016.008
- Thielmann B., Seibt R., Spitzer S. et al. (2013), "Analysis of burnout risks among teachers in GermanUkrainian comparison" [Published in German], ErgoMed. Prakt. Arb. med., 37 (4), 24–31.
- Redlarski G., Lewczuk B., Żak A. et al. (2015), "The Influence of Electromagnetic Pollution on Living Organisms: Historical Trends and Forecasting Changes", BioMed Research International, 18 pages, doi:10.1155/ 2015/234098.
- Gubernsky Yu. D., Goshin M. E., Kalinina N. V. and I. M. Banin. (2016), "Hygienic aspects of electromagnetic pollution of modern dwelling", Hygiene and sanitation, 4. URL: https://europepmc.org/abstract/med/ 27430061 (Accessed 11.10.2018).
- European Commission, Directive 2013/35/ EU of the European Parliament and of the Council of 26 June 2013 on the minimum health and safety requirements regarding the exposure of workers to the risks arising from physical agents (electromagnetic fields) (20th individual Directive within the meaning of Article 16(1) of Directive 89/391/EEC) and repealing Directive 2004/40/EC, 2013/ URL: https://osha.europa.eu/en/ legislation/directives/directive201335euelectromagneticfields (Accessed 11.10.2018).
- Qu T. T., Deng J. X., Li R. L. et al. (2017), "Stress injuries and autophagy in mouse hippocampus after chronic cold exposure", Neural Regen Res, 12 (3), 440–446. https://doi.org/10.4103/1673-5374.202932
- Kolosova O. N. (2015), "Stabilization of homeostasis in rats under the cold influence using ethanol", Bulletin eksper. biologii i meditsiny, 160 (9), 279–283.
- Maslov L. N., Tsybulnikov S. Yu., Naryzhnaya N. V. et al. (2016), "Chronic influence of cold–adaptation without stress", Patologicheskaya fiziologiya i eksper. terapiya, 1, 28–31.
- Vargovic P., Laukova M., Ukropec J. et al. (2018), "Prior Repeated Stress Attenuates ColdInduced Immuno modulation Associated with "Browing" in Mesenteric Fat of Rats", Cell Mol. Neurobiol, 38 (1), 349–361. https://doi.org/10.1007/s10571-017-0531-z
- Dotson G., Maier A., Siegel P. and Anderson S. (2015), "Setting оccupational еxposure limits for chemical allergens: understanding the challenges", J Occup. Environ. Hyg., 1, 82–98. https://doi.org/10.1080/15459624.2015.1072277
- Directive of the Comission 2017/164/EС. On the introduction of the third list of indicative values between limits of occupational exposures (effects), Brussels: European commission; 2017 [cited 2011 March 1]. URL: https://osha.europa.eu/en/legislation/directive/ directive2017164euindicativeoccupationalexposurelimitvalues (Accessed 11.10.2018)
- World Health Organization. Human biomonitoring: facts and figures. 2015, Copenhagen, WHOEuro URL: http://www.euro.who.int/__data/assets/pdf_ file/0007/276388/Humanbiomonitoringfactsfiguresru.pdf (Accessed 11.10.2018).
- Schaufeli W. B., Leiter M. P., Maslach C. and Jackson S. E. (1996), Burnout Inventory General Survey. In: Maslach C, Jackson S E, Leiter M P (Eds). The Maslach Burnout Inventory – test manual. 3rd ed, Consulting Psychologists Press, Palo Alto, CA.
- Kalimo, R., Pahkin, K., Mutanen, P. and ToppinenTanner, S. (2003), "Staying well or burning out at work: work characteristics and personal resources as longterm predictors". Work & Stress, 17, 109–122. https://doi.org/10.1080/0267837031000149919
ORCID ID of co-authors and their contribution to the preparation and writing of the article:
Kapustnik V.A. (ORCID ID 0000-0002-4543-8343) - definition and implementation of tasks for the establishment of professional burnout in workers of socially significant professions in Ukraine, data analysis, formulation of conclusions;
Zavgorodniy I.V. (ORCID ID 0000-0001-7803-3505) - definition and implementation of tasks for the establishment of professional burn-out of servicemen of parts of logistics; research of mechanisms of the combined action of factors; development of methodology of biological monitoring with the establishment of exposition tests and biomarkers effect in the hygienic regulation of xenobiotics; formulating conclusions; registration of the article;
Beckhelmann I. (ORCID ID 0000-0002-3905-3527) - Definition and implementation of tasks for the establishment of professionalthe burnout of workers of socially significant occupations, including the processing of primary material on the software equipment of the "Viennese test systems" and the statistical processing of research data in Germany;
Lytovchenko O. L. (ORCID ID 0000-0002-5286-1705) - determination of the mechanisms of the combined action of electromagnetic radiation under cold stress conditions, statistical processing of data, data analysis, formulation of conclusions, design of the article;
Lalienko O. S. (ORCID ID 0000-0002-9279-1377) - development of methodology of biological monitoring, determination of exposure tests and effects biomarkers, statistical processing and analysis of data, formulation of conclusions, execution of an article.