1(21) 2010

DOI xxxxxxxx

Chernysheva O.N.1, Tkach S.I.2, Melnik O.G.1, Chernova S.D.2, Brykalin V.P.1

MECHANISMS OF SENSITIZATION FORMATION TO TUBERCULOSIS MYCOBACTERIUM IN PATIENTS WITH OCCUPATIONAL RESPIRATORY DISEASES

1Research Institute of Labour Hygiene and Occupational Diseases of Charkov National Medical University

2Charkov Medical Academy of Postdiplome Education, department of Labour Hygiene and Occupational Diseases

Full article (PDF), RUS

Differences in body to tuberculin sensibilization in patients with coniotuberculosis are revieled by chemoluminescence method in vitro in non active and active their course. The indices of chemoluminescence in patients with chronic obstructive lung diseases show immunologic deficiency state, and in silicosis patients the indices are higher. However, substantional decreasing (by 2 times) of cell sensitivity to tuberculin can be a cause of tuberculosis development in future.Revealed differences are closely connected wich changes of the character in cell composition of peripheral blood of the whole patient groups. The nosology of each disease depende on differences in the work conditions.

Key words: dust pollution, occupations machinebuilding workers, to tuberculin sensitivity, respiratory pathology

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