4(24) 2010

DOI xxxxxxxx

Remennyk О. L, Varyvonchyk D. V.

MORPHO-FUNCTIONAL CRITERIA OF RISK DEVELOPMENT AND PREVENTION OF NEOPLASMS IN BRONCHI AND LUNGS AMONG OCCUPATIONAL PATIENTS EXPOSED TO DUST, CONTAINING CRYSTAL SILICA

SI «Institute for Occupational Health of AMS of Ukraine», Kyiv

Full article (PDF), UKR

The risk of development of bronchi and lungs cancer (BLC) in workers, exposed to dust containing SiO2, is characterized by a long-term course of pneumoconiosis (PC), chronic bronchitis (CB), chronic obstructive lung disease (COLD). To morpho- functional signs, which contribute to high risk of BLC development in patients, the occurrence and progress of the following dis¬orders in patients with PC can be referred: diffusive pneumosclerosis, emphysema, interstitial (s-type) and nodular (p-nodular) changes, addition of the tuberculosis process and development of the mixed type of lungs insufficiency; in patients with CB and COLD — development of the diffusive pneumosclerosis, lungs insufficiency of mixed or obstructive types. A three-step system of actions has been proposed, directed at prophylaxis and early diagnostics of BLC in patients with PC, CB and COLD.

Key words: SiO2, bronchi and lungs cancer, pneumoconiosis, chronic bronchitis, chronic obstructive lung disease, risk factors, prevention

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