https://doi.org/10.33573/ujoh2008.01.077
Dobrovolsky L.A.1 Belashova I.G.1 Radvanska E.S.2
POLYCYCLIC AROMATIC HYDROCARBONS AND OCCUPATIONAL LUNG CANCER (REVIEW OF FOREIGN LITERATURE)
1Institute for Occupational Health of AMS of Ukraine, Kyiv
2A.A. Bohomolets National Medical University, Kyiv
Full article (PDF), RUS
The review of foreign literature is devoted to occupational cancer issues. The authors take a retrospective look at these issues, and discuss information about polycyclic aromatic hydrocarbons (PAH) including PAH generation at various production processes, PAH working place concentrations as well as epidemiologic data, biomarkers and carcinogenic mechanisms.
Key words: polycyclic aromatic hydrocarbons; occupational lung cancer; history; epidemiology; biomarkers; mechanisms of action
References
- Alfred L.J. Differential inhibition of DNA and RNA synthesis induced in cultured mammalian cells by 12- dimethylbenz (o)anthracene // Nature.- 1965.-V. 208.- P. 1939-1941. https://doi.org/10.1038/2081339a0
- Ates 1. Determination of exposure to polycyclic aromatic hydrocarbons in some work groups in TUrkey by measurement of 1-hydroxypyrene levels In urine // Bull. Environ. Contam. Tbxicol.- 2004.- V. 73. № 2,- P. 242-248. https://doi.org/10.1007/s00128-004-0419-8
- Berger J., Manz A. Cancer of the stomach and the colon-rectum among workers in a coke gas plant // Am. J. Ind. Med.- 1992,-V. 22.-P. 825-834. https://doi.org/10.1002/ajim.4700220605
- BosettiC., BoffettaP., LaVecchieaC. Occupational exposures to PAH and respiratory and urinary tract cancers: a quantitative review to 2005 // Ann. Oncol.- 2006.- № 8.- P. 25.
- Bostrom C.E., Gerde P. , Hanberg A. Cancer risk assessment, indicators and guidelines for PAH in the ambient air // Environ. Health Perspect.- 2002,- V. 110.- P. 53-60. https://doi.org/10.1289/ehp.02110s3451
- Bridbord K., Finklea J.F.. Wagner J.K. Human exposure to polynuclear aromatic hydrocarbons. In: Freudental R.I., Jones P. W., eds. Carcinogenesis - A comprehensive survey. Vol. 1. Polynuclear aromatic hydrocarbons, chemistry, metabolism and carcinogenesis, NewYourk, Ravel Press. 1976.-P. 319-324.
- Cavaliery E.L.. Rogan E.G. The approach to understanding aromatic hydrocarbon carcinogenesis. The central role of radical cations in metabolic activation // Pharmacol. Then- 1992,- V.55,№ 2.- P. 183-199. https://doi.org/10.1016/0163-7258(92)90015-R
- Cavallo D. Assessment of exposure to RAH during road paving // G. Ital. Med. Lav. Ergon.- 2003.- V.25,Suppl.3.- P. 98-99.
- Christian H.H. Cancer of the lung in employees of a public utility. A fifteen-year study (1946-1962) // J. OccuP. Med.- 1962,-V.4,№ 3.-P. 133-139.
- Conney A. Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons // Cancer Res.- 1982.- V. 42.- P. 4875-4917.
- Constantino J.P.. Redmont C.K., Bearden A. Occupationally related cancer risk among coke oven workers // J. OccuP. Environ. Med.- 1995.- V.37.- P. 597-604. https://doi.org/10.1097/00043764-199505000-00009
- Dinman B.D. Aluminium, alloys and compounds // Encyclopaedia of Occupational Health and Safety. Vol. 1, Geneva. ILO, 1983.- P. 131-135.
- Doll R. Br. J. Industr. Med. 1952.-V. 9,- P. 180. https://doi.org/10.1136/oem.9.3.180
- Doll R., Fisher R.E.W., Gammon E.J. Mortality of gas workers with special reference to cancers of the lung and bladder, chronic bronchitis and pneumoconiosis // Brit. J. Industr. Med - 1965.-V 22, № l.-P. 1-12. https://doi.org/10.1136/oem.22.1.1
- Elovaara E., Vaananen V., Mikkola J. Naphtols, phananthrols, and 1 -hydroxyperene as urinary biomarkers of PAH esposure // Drag. Metal Rev.- 2002,- V. 35. suppl. 1.- P. 29-31.
- Emmet E.A., Bingman E.M., Barkley W. A carcinogenic bioassay of certain roofing materials // Am. J. Ind. Med.- 1981,-V. 2.-P. 59-64. https://doi.org/10.1002/ajim.4700020110
- Forastier F., Pupp N.. Magliola E. Respiratory cancer mortality among workers employed in thermoelectric power plants // Scand. J. Work. Environ. Health.- 1989.-V. 15.-P. 383-386. https://doi.org/10.5271/sjweh.1835
- Gajdosova D., Gaidos O., Justova Z. Chromosomal aberrations associated with exposure to polycyclic aromatic hydrocarbons among coke production employees // Tbxicol. Lett.- 2001.- V. 123, suppl. 1.- P. 30.
- Gerarde H.W. Asphalt // Encyclopaedia of Occupational Health and Safety. Vol. 1. Geneva, ILO. 1989,-P. 198-200.
- Gross D., Konetzke G.W., Schmidt E. On the industrial hygienic situation of mastic asphalt finishers with special reference to the carcinogenic action of tar, asphalt and bitumen // Z. ges. Hyg.- 1979,- V. 25,- P. 655-659.
- Guillemin M.P., Herrera H., Huynh C.K. Occupational exposure of truck drivers to dust and polynuclear aromatic hydrocarbons: a pilot study in Geneva. Switzerland // Int. Arch. OccuP. Environ. Health.- 1992.-V. 63, № 7,- P. 439-447. https://doi.org/10.1007/BF00572109
- Gustavsson P., Reuterwall C. Mortality and incidence of cancer among Swedish gas workers // Brit. J. Ind. Med.- 1990,-V. 47,-P. 169-174. https://doi.org/10.1136/oem.47.3.169
- Hammond E.C., Selikoff I.J.. Lawther P. L. Inhalation of benzpyrene and cancer in man // Ann. NY Acad. Sci.- 1976,-V. 271,-P. 116-124. https://doi.org/10.1111/j.1749-6632.1976.tb23100.x
- Hansen E.S. Mortality from cancer and ischemic heart disease in Danish chimney sweeps: a five-year follow-up//Am. J. Epidemiol.- 1983.-V. 1 l.-P. 356-361. https://doi.org/10.1093/oxfordjournals.aje.a113526
- Harvey R.G., Halonen M. Interaction between carcinogenic hydrocarbons and nucleosides // Cancer Res.- 1968,-V. 28, № l.-P. 2183-2186.
- Health survey of former workers in a Norwegian coke plant // OccuP. Environ. Med.- 1989.- V. 52.- P. 622-626.
- Hecht S.S. Human urinary carcinogen metabolites - biomarkers for investigating tobacco and cancer // Carcinogenesis.- 2002,- V.23.№ 6.- P. 907-922. https://doi.org/10.1093/carcin/23.6.907
- Hemminki K. Nucleic acid adducts of chemical carcinogens and mutagens // Arch. Toxicol.- 1983.- V.52.-P. 249-285. https://doi.org/10.1007/BF00316495
- Hesse O. Beruflische langenkrebs // Arch, fcr Heilkunde.- 1878,- 13.5. Hl.-P. 50-56. https://doi.org/10.1007/BF01991415
- Hoffman F.l. The occupational incidence of cancer.- Geneva, 1931.- 23 p.
- Hooiveld M. Lung cancer mortality in a Dutch cohort of asphalt workers: evaluation of possible confounding by smoking // Am. J. Ind. Med.- 2003 - V.43. № l.-P. 79-87. https://doi.org/10.1002/ajim.10141
- Hueper W.C. Occupational tumors and allied diseases. Springfield. 111. Ch.C. Thomas Publishing House, 1942.- 896 p.
- Hygiene du Travail. Ttimeurs professionelles. Bureau Intern, du Travail. Series № 130.- Geneve, 1927,-P. 1-21.
- IARC monographs on the evaluation of the carcinogenic risk of chemicals in humans.- Lyon.- 1984.- V. 34.- P. 37-64.
- IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans.- Lyon.- 1982,- V. 1-29. suppl. 4.-P. 14-15.
- IARC monographs on the evaluation of the carcinogenic risks of chemicals to humans. Vol. 65. Printing processes and printing inks, carbon black and some nitro compounds. Lyon.- 1996,- P. 127-128, 245-246.
- IARC Sci. Publ. № 83. Long-term and short-term assays for carcinogenesis // Eds.: R. Montesano et alLyon. 1986,-P. 129-138.
- Iba M.M., Wei C.. Weyand E.H. Inducibility ofCYP 1A expression in cultured human lung explants // Drug. Metal Rev-2001.-V. 33. suppl.l.-P. 143-144.
- Kaufman W.K.. Rahija R.J.. MacKenzie S.A., Kaufman D.G. Cell cycle-dependent initiation of hepa- tocarcinogenesis in rats by 7r,8t-dihydroxy-9t,lOt- epoxy-7,8,9,10-tetrahydrobenzo (a)pyrene // Cancer Res.- 1987.-V. 47,-P. 3771-3775.
- Kennaway E.L. On cancer-producing tars and tar-fractions // J. Industr. Hyg.- 1923-1924.- V. 5.- P. 462-465.
- Kennaway E.L., Hieger I., Cook J.W. The production of cancer by pure hydrocarbons // Proc. Roy Soc. B.- 1932,-V. 11 l.-P. 455-460.
- Khesina A.Ya.. Tblcheev Y.D., Chykovani G.P. The content of polycyclic aromatic hydrocarbons in coke process effluents and mutagenic effect of extracts from soot // ExP. Oncol.- 1985.-V. 7, № 2,- P. 26-28.
- Koelsch F. Neubildungen und Beruf// Handbuch der Berufs Kraukheiten Bd. I., Jena, I935.-P. 1-621.
- Kuroda S. Industr. Med. Surg.- 1937.- V.6.- P. 304.
- Lawther P. J., Commins B.T.. Waller R.E. A study of the concentrations of polycyclic aromatic hydrocarbons in gas works retort houses // Brit. J. Industr. Med.- 1965.-V.22, № l.-P. 13-20. https://doi.org/10.1136/oem.22.1.13
- Leon D.A., Thomas P.. Hutchings S. Lung cancer among newspaper printers exposed to ink mist: a study of trade union members in Manchester, England // OccuP. Environ. Med.- 1994,-V.5l.-P. 87-94. https://doi.org/10.1136/oem.51.2.87
- L’Epee P. , Lazarini H.J., Doignon J. Tar and pitch // Encyclopaedia of Occupational Health and Safety. Vol. 2. Geneva. ILO, 1983.- P. 2147-2149.
- Lesage J. Evaluation of worker exposure to polycyclic aromatic hydrocarbons // Am. Ind. Hyg. Assoc. J.- 1987,-V. 48, № 9,- P. 753-759. https://doi.org/10.1080/15298668791385525
- Knecht U. Gaseous and adsorbed PAH in an iron foundry // Br. J. Ind. Med.- 1986,- V. 43, № 12,- P. 834-838. https://doi.org/10.1136/oem.43.12.834
- Liu N.. Wang Z., Dong D. Cancer mortality among carbon workers in China: retrospective cohort study // J. OccuP. Health.- 1997.-V.39.-P. 325-330. https://doi.org/10.1539/joh.39.325
- Logan W.P. D. Cancer mortality by occupation and social class, 1851-1971. IARC Sci. Publ. № 36 - London - Lyon. IARC. 1982,- 253 p.
- Lu Q.F. Co-detection of P21. P53 and HSP70 and their possible role in diagnosis of PAHs-related lung cancer // Zhonghua Lao Dong Wei.- 2003.- V.21 ,№ S.- Р. 359-361.
- Lundgren K. Cytogenetic and chemical detection of human exposure to polyhalogenated aromatic hydrocarbons // Environ. Mol. Mutagen.- 1988.-V. 11, № 1 .P. 1-11. https://doi.org/10.1002/em.2850110103
- Lynge E., Andreassen R.B.. Villadsen E. Cancer in printing workers in Denmark // OccuP. Environ. Health.- 1995.-V. 52.- P. 738-744. https://doi.org/10.1136/oem.52.11.738
- Makhniashvili I., Szewezynska M., Ekiert E. Occupational exposure to carcinogenic substances during iron foundring processes // Med. Pr.- 2006.- V.57. №2.-P. 133-138.
- Malaiyandi M. Benedek A., Holko A.P. . Bancsi J.J. Measurement of potentially hazardous polynuclear aromatic hydrocarbons from occupational exposure during roofing and paving operations. In: Cooke M.A.O., eds. Polynuclear aromatic hydrocarbons: physical and biological chemistry, 6th International symposium, Columbus.- 1982,-P. 471-489.
- McDonald J.D. Generation and characterization of four dilutions of diesel engine exhaust for subchronic inhalation study // Environ. Sci. Tbxicol.- 2004,- V.38, № 9,- P. 2513-2522. https://doi.org/10.1021/es035024v
- Milham S. Occupational mortality in Washington state 1950-1979 (Contract № 210-80-0088). NIOSH.- 1982.-P. 1257.
- Monarca S. Application of the Salmonella mutagenicity assay to PAH in workplaces exposed to petroleum pitch and petroleum coke // Int. Arch. OccuP. Environ. Health.- 1982.-V. 49, № 3-4.- P. 223 -239. https://doi.org/10.1007/BF00377932
- Moss E., Scott T.S., Atherley G.R.C. Mortality of newspaper workers from lung cancer and bronchitis. 1952-1968 // Br. J. Ind. Med.- 1972.-V.29,-P. 1-14. https://doi.org/10.1136/oem.29.1.1
- Moulin J.J., Wild P. , Mur J.M. Risk of lung, larynx, pharynx, and buccal cavity cancer among carbon electrode manufacturing workers // Scand. J. Work. Environ. Health.- 1989,-V. 15,-P. 30-37. https://doi.org/10.5271/sjweh.1885
- Mukheijee S. Smoking status and occupational exposure affects oxidative DNA injury in boiler-makers exposed to metal fume and residual oil fly ash // Cancer Epidemiol. Biomarkers Prev.- 2004.- V. 13. № 13,-P. 454-460.
- Nilsson R. Increased urinary excretion of 8- hydroxydeoxyguanosine in engine room personnel exposed to polycyclic aromatic hydrocarbons // OccuP. Environ. Helath.- 2004,- V. 61. №8.-P. 692-694. https://doi.org/10.1136/oem.2003.007435
- Perera F. Biomarkers and molecular epidemiology of occupationally related cancer // J. Toxicol. Environ. Health.- 1993,- V. 40, № 2-3,- P. 203-215. https://doi.org/10.1080/15287399309531788
- Phillip D.H. Monitoring occupational exposure to carcinogen detection by 32P-postlabeling of aromatic DNA adducts in white blood cells from iron foundry workers // Mutat. Res.- 1988,-V.204, № 3,- P. 531-541. https://doi.org/10.1016/0165-1218(88)90047-X
- Poirier M.C. Chemical induced DNA damage and human cancer risk // Nat. Rev. Cancer.- 2004.- V. 4. № 8,- P. 630-637. https://doi.org/10.1038/nrc1410
- Pott F., Heinrich U. Neue erkenntnisse uber die krebserzengende Wirkung von Dieselmotorabgas // gesamte Hyg.- 1988.- 13.34, № 12.- P. 686-689.
- Pullman B., Pullman A. Quantum biochemistiy. / New York, Interscience, 1963.- 215 p.
- Purdham J.T., Bozek P. R.. Sass-Kortsak A. The evaluation of exposure of printing trade employees to polycyclic aromatic hydrocarbons // Ann. OccuP. Hyg.- 1993,-V. 37.-P. 35-44.
- Re M. Exposure to polycyclic aromatic hydrocarbons in industrial use of mineral oils: a method of risk evaluation// Med. Lav.- 1982.-V. 73. №2.-P. 140-146.
- Verma D.K. Polycyclic aromatic hydrocarbons in Ontario foundry environments // Ann. OccuP. Hyg.- 1982.-V.25, № l.-P. 17-25.
- Robertson J. A mortality study of carbon black workers in the United States from 1935 to 1974 // Arch. Environ. Health.- 1980.-V. 35.-P. 183-186. https://doi.org/10.1080/00039896.1980.10667489
- Robertson J. Epidemiological studies in North American carbon black workers // Ingal. Toxicol.- 1996.-V. 8 (suppl).— P. 41-50.
- Robertson J., Ingalls T.H. A case-control study of circulatory, malignant respiratory morbidity in carbon black workers in the United States // Arch. Environ. Health.- 1978.-V. 33.-P. 241-246.
- Romundstad P. R.. Anderson A., Haldorsen T. Cancer incidence among workers in six Norwegian aluminium plants // OccuP. Environ. Med.- 2000.-V. 26.- P. 461-469. https://doi.org/10.5271/sjweh.569
- Savochkina I.V., Likhachev A.Ya. Fundamentals and approaches to predicting individual sensitivity to carcinogenic action of polycyclic aromatic hydrocarbons // Vopr. Onkol.- 1989,- V. 35, № 4- P. 407-415.
- Schamberg J. Tltmors of occupational origin and occupational cancer // Encyclopaedia. Hygiene, Pathology and Social Welfare. Vol. II (i-z). London, 1934,-P. 1139.
- Schimberg R.W., Pfaffi P. , Tossavainen A. Polycyclic aromatic hydrocarbons in foundries // J. Tbxicol. Environ. Health.- 1994 - V.6.- P. 1187-1194. https://doi.org/10.1080/15287398009529936
- Schwerin J. Blastengeschwulste bei Arbaitem in chemischen Betriebe // Zbl. Gewerbehyg. u. Unfall. 1920, Januar.- P. 64.
- Schoket B. Covalent binding of components of coal-tar, creosite and bitumen to DNA of the skin and lungs of mice following topical application // Carcinogenesis.- 1988-V. 9. № 7 - P. 1253-1258. https://doi.org/10.1093/carcin/9.7.1253
- Shields P. G., Bowman E.D., Harrington A.M. Polycyclic aromatic hydrocarbon-DNA adducts in human lung and cancer susceptibility genes // Cancer Res.- 1993,-V. 53, № 15.- P. 3486-3492.
- Singer B., Grunberger D. Molecular biology of mutagens and carcinogens. Plenum Press. New York. London. 1983.-347 p. https://doi.org/10.1007/978-1-4613-3772-0
- Sollenberg J. Polycyclic aromatic hydrocarbons / / Encyclopaedia of Occupational Health and Safety. Vol. 2. Geneva, 1LO, 1983,-P. 1755-1759.
- Sorahan T.. Hamilton L., Van Tonheren M. A cohort mortality study of U.K. carbon black workers 1951-1996 // Am. J. Ind. Med.-2001-V. 39-P. 158-170. https://doi.org/10.1002/1097-0274(200102)39:2<158::AID-AJIM1003>3.0.CO;2-L
- Spinelli J.J., Band P. R.. Svirchev L.M. Mortality and cancer incidence in aluminum reduction plant workers //J. OccuP. Med - 1991.-V. 33- P. 1150-1155. https://doi.org/10.1097/00043764-199111000-00011
- Steinegger A.F. Exposure to polycyclic aromatic hydrocarbons in an anode plant and potrooms // Med. Lav.- 1981,- V. 72, № 4,- P. 259-265.
- Stukonis M.K. Modem statistical methods of study of malignant tumors epidemiology in England // Epidemiology of Malignant Tiunors. Alma-Ata, «Nauka», 1970.-P. 21-27.
- Sutherland R. ... cited by R. Doll // Brit. J. Ind. Med. V.16.- 181 p.
- Swaen G.M., Slangen J. Mortality in a group of tar distillery workers and roofers // Int. Arch. Occup. Environ. Health.- 1997,-V. 70.-P. 133-137. https://doi.org/10.1007/s004200050197
- Tfeutschlaender J. Die Berufkrebse // Zeitsehrift fur Krebs.- 1930.- Bd.32,H.№ 6,- P. 106-112. https://doi.org/10.1007/BF01636820
- Teutschlaender J. Ueber den Pechkrebs der brikettarbaiter // Zeitsehrift fur Krebs.- 1929.- Bd.30, H. 58.-P. 905-910.
- Tola S., Koskela R.S., Hemberg S. Lung cancer mortality among iron foundry workers // J. Occup. Med.- 1979,-V. 21.- P. 753-759. https://doi.org/10.1097/00043764-197911000-00010
- Tbmquist S. Up-take, metabolism and DNA- binding of the chemical carcinogens benzo (A)-pyrene and 2-nitrofluorene in the rat lung. Stockholm. 1989.
- Vyskocil A. Risk assessment of lung cancer to environmental PAH pollution sources // Hum. ExP. Tbxicol.-2004.-V. 23, № 3.-P. 115-127. https://doi.org/10.1191/0960327104ht429oa
- Wolff J. Die Lehre v.d. Krebskrankheit. Ill Tteil. I Abteil. Jena, Fisher. 1913.- P. 56-57.
- Xu Z., Brown L.M., Pan G.W. Cancer risks among iron and steel workers in Anshan, China. Part 2: Case- control studies of lung and stomach cancer // Am. J. Ind. Med.- 1996.- V. 30,- P. 7-15. https://doi.org/10.1002/(SICI)1097-0274(199607)30:1<7::AID-AJIM2>3.0.CO;2-#