2(39) 2014

DOI xxxxxxxx

Chyrva O. V.


SI «National Institute of Therapy named after L.T. Malaya of NAMS of Ukraine», Kharkiv

Full article (PDF), UKR

Introduction. The main directions of preventive medicine are to establish the risk factors for chronic non-communicable social diseases, to study the constitutional-typological characteristics of different populations (somatotype), to assess body’s func-
tional adaptation reserves by noninvasive techniques and to correct the prenosological deviations in due time. The problem of health status of young persons is rather actual.
The aim was to improve the efficiency of prevention of the functional pathology among the organized student population by assessing the role of the main trigger factors of lifestyle in young adults.
Materials and methods. The study was performed on 305 persons (125 males, 180 females) of mean age 20,3 ± 0,2. All patients were divided into two groups: I — persons with NCD cardiac form (study group), II - healthy subjects (control group). Depending on the presence of functional disorders in the digestive system (FDDS) the following subgroups were formed: patients with the established functional dyspepsia (NCD + functional dyspepsia) (n = 68), irritable bowel syn¬drome (NCD + irritable bowel syndrome) (n = 36), biliary dyskinesia (NCD + biliary dyskinesia) (n = 11), students with NCD and without FDDS were included in the comparison group (n = 82).
Results. Almost 60,0 % patients consider non-rational nutrition as the main cause of their disease and 1/3 - chronic psycho-emotional stress. The significant relationship was established in the development of FDDS and the next trigger factors: avail¬ability of chronic emotional stress (71,9 %, p = 0,012), poor nutrition (78,1 %, p = 0,031), poor intake of the drinking water (50 %, p < 0,001), fresh fruits and vegetables (30,2 %, p = 0,014), presence of food poisonings in the medical history (51 %, p = 0,004) and food allergies (25 %, p = 0,008), use of drugs (mostly - non-steroidal anti-inflammatory drugs) (43,8 %, p = 0,002).
Conclusions. Almost 60 % of the surveyed persons of the organized student population expressed signs of NCD. The FDDS were diagnosed in more than half of patients with NCD. The main trigger factors of FDDS in patients with NCD were use of alcoholic beverages, long intervals between meals, lack of using the drinking water, food poisonings and the presence of food allergy in the medical history, use of drugs (especially non-steroidal anti-inflammatory drugs).

Key words: functional disorders, population of students, lifestyle, risk factors, prevention


    1. Arutyunov, G. P. 2010, Treatment of risk factors in cardiovascular diseases. Moscow: GEOTAR-Media, 672 p., pp 27-28 (in Russian).
    2. Yesaulenko, I. E., Zuikova, A. A., Petrova, T. N. 2013, «Assessment of the character of nutrition and its role in formation of risk factors in chronic non­communicable diseases among medical students», Preventive medicine, Vol. 16, no. 2, pp. 40-41 (in Russian).
    3. Zhukova, M. A., Parkhomenko, A. A., Bakhteyeva, F. R. 2013, «Smoking among young people as part of their lifestyle: main tendencies and search for solution of the problem», Preventive medicine, Vol. 16, no. 2, pp. 45 (in Russian).
    4. Tarantsova, A. V. 2013, «Prenosological diagnostics in practice of a physician- practitioner», Preventive medicine, Vol. 16, no. 2, pp. 132-133 (in Russian).
    5. Tsaralunga, V. N., Prokopchuk, S. N., Semenyuk, A. S. 2013, «Memorandum for a patient with the syndrome of irritable intestine», Therapia. Ukrainsky medychnyi visnyk, no. 1 (76), pp. 58-60 (in Russian).
    6. Gore, F. M., Bloem, P. J., Patton, G. C. 2011, «Global burden of disease in young people aged 10-24 years: a systematic analysis», Lancet, June 18; no. 377 (9783), pp. 2093-102.
    7. Kazutoshi, H., Takayuki, M., Hiroto, M. 2009, «Analysis of the Gastrointestinal Symptoms of Uninvestigated Dyspepsia and Irritable Bowel Syndrome», Gut and Liver, Vol. 3, no. 3, pp. 192-196.
    8. Sarnelli, G., De Giorgi, F., Atteo, E. et al. 2010, «Frequency, symptom evolution and pathophysiological correlates in prospectively identified patients with post­infectious dyspepsia», DDW - New Orleans, Abstract M.
    9. Thabane, M., Kottachchi, D. T., Marshall, J. K. 2007, «Systematic review and meta-analysis: The incidence and prognosis of post-infectious irritable bowel syndrome», Aliment Pharmacol Ther, no. 26 (4), pp. 535-544.
    10. Walker, M. M., Salenian, S. S., Murray, C. E. et al. 2010, «Implications of eosinophilia in the normal duodenal biopsy - an association with allergy and functional dyspepsia», Alimentary Pharmacology & Therapeutics, no. 11 (31), pp. 1229-1236.