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RESEARCH OF NEURON SENSITIVITY TO MERCURY CHLORIDE IN VITRO

DOI xxxxxxxx

Sokurenko L.M.

RESEARCH OF NEURON SENSITIVITY TO MERCURY CHLORIDE IN VITRO

O.O. Bogomolets National Medical University, Kyiv

Full article (PDF), UKR

Cytotoxicological action of mercury chloride was studied in the cultures of cells IMR-32 (human neuroblastoma). The influ-ence of different doses of mercury chloride on survivability and proliferation of neurons in the cell culture in different degree was studied. In doses 1000 and 100 MkM/Ml cytotoxical effect was more expressed, and at doses 1 and 0,1 MkM/Ml — inhibi¬tion of proliferation occured, both pathological mechanisms were observed in the dose 10 MkM/Ml.

Key words: intoxication, mercury chloride, micromercurialysm, cell culture, nervous tissue, neuron

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