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Assessment of the contribution of titanium-containing nanomaterials using the test system of Secale cereale L. for screening studies of potential hazard

ISSN 2223-6775 Ukrainian journal of occupational health Vol.19, No 2, 2023

Assessment of the contribution of titanium-containing nanomaterials using the test system of Secale cereale L. for screening studies of potential hazard

Patyka T.I.1, Demetska O.V.1, Beliuha O.G.1, Movchan V.O.1, Balia A.H.2
1SI "Kundiev Institute of Occupational Health of National Academy of Medical Sciences of Ukraine", Kyiv, Ukraine
2College of Pharmacy, University of Michigan, Ann Arbor, United States of America

Full article (PDF): ENG / UKR

Introduction. Doping is a widely used method of modifying nanoparticles to enhance their electrical, optical, and biological activity. Doping with heavy metals can increase the initial toxicity of the nanomaterial, and therefore negatively affect the health of workers and cause pollution of environmental objects.

The purpose of research. To assess the potential toxic effect of additional doping of titanium-containing nanopowders with heavy metals (silver) on the plant test system Secale cereale L.

Materials and methods of research. In a model laboratory experiment, the phytotoxicity of titanium dioxide doped with silver (nanocomposite TiO2+Ag, mass fraction Ag~4%), titanium dioxide complex doped with silver (nanocomposite TiO2+Ag, mass fraction Ag~8%) and nanopowder of titanium dioxide (TiO2), synthesized by the method of thermal decomposition in a glucose-citrate buffer (1 glucose : 4 sodium citrate) using the example of Secale cereale L. (rye) seeds.

Results. The determination of morphometric (biometric) indicators of the test object (Secale cereale L.) demonstrated that the growth processes of the studied plants were inhibited in almost all variants with nanomaterials.

Conclusions. It was established that the growth processes of the studied plants are inhibited in almost all variants with titanium-containing nanomaterials. Under the exposure to titanium dioxide and nanocomposite TiO2-Ag (4.0%) there is a decrease in the value of the test function in the experiment in comparison with the control in the range from low to medium when used as a test object as seed rye seedlings, and bovine spermatozoa.

Keywords: titanium-containing nanomaterials, doping, phytotoxicity.


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