HYGIENIC EVALUATION OF WORKING CONDITIONS IN PESTICIDES APPLICATION: POSSIBILITIES OF ALTERNATIVE APPROACH
Institute for Occupational Health of AMS of Ukraine, Kyiv
Full article (PDF), UKR
Nowadays, hygienic regulation of safe use of pesticides in agriculture requires a substantial revision, because of the existence of a number of provisional pesticide standards for the working zone air and due to unavailability of acceptable regulation levels for operator's skin contamination. The solution of this task with the use of «classic* technologies for experimental grounding of standards appears to be not rational, taking into account the intensity of work. The constructive alternative of such technology is in the use of methodology for risk assessment, modem risk assessment exposure models for pesticides applicators, in particular. Under such approach the integral acceptable operator exposure levels (AOELs) are the supporting criteria of safety, determined basing on the analysis of the aggregate of toxicological data with the use of the proposed algorithm. Working out of hygienic standards for pesticides for the working environment with the use of AOELs and with due into account of peculiarities of the toxic effect of pesticides under different ways of entering into the human body will promote further development of the discussed approach.
Key words: pesticides, work conditions, hygienic standards, risk assessment, acceptable operator exposure levels, evaluation algorithm, prospects of hygienic regulation of pesticides
- Permissible doses, concentrations, quantities and levels of pesticide content in agricultural raw material, food products, working zone air, atmospheric air, water, ground (2001), State sanitary rules and norms 126.96.36.199.3.4-000-2001, Kiev, 242 p.
- Katsnelson B.A.. Privalova L.I. (1996), “Risk assessment and hygienic regulation - alternative or complementary approaches”, Toksikol. vestnik, 4, 5-10.
- Kirsenko V.V., Yastrub T.O. (2004), “Methodical approaches to hygienic assessment of work conditions in the use of pesticides in modern conditions”, Dovkillya ta zdorovya, 4, 51-55.
- Criteria of risk assessment of harmful effect of modern pesticides on workers (to the grounding of hygienic norms and preventive measures) (2004), Report on the scientific work (final), Institute of Occupational Health, № 0102 І.U02090, Kyiv, 161 p.
- Kundiiev Yu.I., Kirsenko V.V., Yastrub T.O. (2000), Ratio of pesticide toxicity when administered per os and applied to the skin in assessing the degree of their danger”, Sovremen. problemy toksikologii, 3, 11-15.
- Kundiiev Yu.I., Kirsenko V.V., Yastrub T.O. e.a. (2002), “Algorithm for determining the exposure dose in the skin resorptive intake of pesticides during their use”, Collection of papers Hyhyena truda, Issue ЗЗ, 240-248.
- Kundiiev Yu.I., Kirsenko V.V., Yastrub T.O. e.a. (2002), “Use of the allowable daily dose as a criterion for assessing the risk of adverse effects of pesticides when they are used by workers”, Zhurnal AMN Ukrainy, 8 (4), 763-769.
- Kundieev Yu.I., Kirsenko V.V., Yastrub T.O. (2004), Ways of practical use of the allowable daily dose in assessing the risk of exposure to pesticides on workers”, Collection of papers Hyhyena truda, Issue.35, 146-157.
- Metodicheskiye ukazania po gigienicheskoi otsenke novykh pestitsidov [Methodical instructions on hygienic assessment of new pesticides]. (1988), VNIIGINTOKS, Kiev, 212 p.
- Yastrub T.O. (2001), Skin resorption effect in hygienic assessment of work conditions in pesticide use, Abstract of cand. med. sci., Hygiene, Institute of Occupational Health, Kyiv, Ukraine.
- Council Directive of 15 July 1991 concerning the placing of plant protection products on the market (91 / 4 14/ EEC), Offlcial J. of the European Communities.
- Lundehn J. Krebs B. (1992), “Uniform principles for safeguarding the health of applicators of plant protection products”, Kommissionsverlag P.Parey, Berlin, Germany.
- Risk assessment in the Federal Government: managing the process (1995), US NRC (US National Research Council), C. National Academy Press, Washington, USA.
- Principles for Assessment of Risk to Human Health from Exposure to Chemicals. (1999), No 210, WHO, Geneva, Switzerland.